Planning a cruise that departs from Genoa? There’s good news for travelers coming from Tuscany: as of April 2025, Itabus has launched new long-distance bus routes connecting key Tuscan cities — including Florence, Pisa, Lucca, Siena, and Pistoia — directly to Genoa.
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Direct Buses from Tuscany to Genoa with Itabus
Here are the launch fares for the new routes:
Route | Fares from | Book Online |
---|---|---|
Florence – Genoa | €9.97 | book here |
Pisa – Genoa | €9.97 | book here |
Lucca – Genoa | €9.97 | book here |
Siena – Genoa | €9.97 | book here |
Pistoia – Genoa | €9.97 | book here |
Each link takes you directly to the corresponding route on the official Itabus website.
Itabus offers multiple departures daily, with modern coaches, free Wi-Fi, and panoramic seating options. It’s an ideal alternative to train travel — especially for those carrying luggage or looking for a more direct ride.


Why You Should Arrive in Genoa the Day Before Your Cruise
🔎 Search here for the best places to stay in Genoa and enjoy a stress-free night before your cruise!
If your cruise departs from Genoa, it’s highly recommended to arrive at least one day in advance. Unexpected events — like strikes, highway delays, or demonstrations — can disrupt same-day travel plans. By staying overnight in Genoa, you avoid unnecessary stress and give yourself time to enjoy the city.

Some great places to visit include the Genoa Aquarium, the Museum of Italian Emigration, Christopher Columbus’ House, or even the famous Teatro Carlo Felice. You might also consider taking the city’s hop-on hop-off bus to discover Genoa’s top attractions.
Bus Routes from Tuscany to Genoa
Whether you’re boarding a cruise or just planning to explore the Ligurian coast, Itabus’ new routes from Tuscany to Genoa offer flexibility, comfort, and excellent prices.

Just remember: plan ahead and book your overnight stay in Genoa before your cruise — your future self will thank you.
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